I dont know, i have this feeling that combat anomalies in high sec pay more than high sec security missions…
Combat Anomalies in high sec usually dont have a faction spawn or escalation, but when you do get one, sometimes you get a 100 mil or 200 mil module or implant that sells to buybacks such as JitaRun and EC Trade for 80 mil or 180 mil, or around that,
which is pretty good considering you get that money in 2-24 hours, instead of hauling to a trade hub to get killed with it and make nothing, or survive and wait for it to sell, which might never sell because of market traders and bots constantly undercutting you every 1 second.
And if you do high sec combat anoamlies in a tech 1 cruiser, instead of tech 1 frigate with tech 1 modules,
you might be able to do them faster, especially the weaker ones like hideaway and burrow, and get faction spawns and escalations faster, meaning more chances at a 100-200 mil module or implant.
Security missions, on the other hand, you can only do up to Level 3 security missions. Level 4 and 5 require paying real life money, or spending hundreds of millions of ISK on a omega membership that only lasts a month.
And the Level 3 security mission is full of cruisers and battlecruisers, so doing it in a tech 1 frigate is slow, and level 2 and 3 security missions dont pay enough to get a cruiser, unless you want to do them for days and days.
Cant use destroyers because destroyers are slow, fragile, and have the same tank as frigates, so you will die fast.
In a tech 1 frigate, you can either run Level 2 security missions, or maybe Level 3, and make a bit of money,
Or you can run combat anomalies in high sec, still getting bounty and npc drops, though less than Level 3, but also every once in a while get a 100 - 200 mil drop from either the faction spawn in the combat anomaly, or the escalation the combat anomaly gives.
===============================================================================
Though i do understand that 100 - 200 mil drop is really lucky. and faction spawns and escalations are a once in a while thing, not frequent.