Low sec was the last focus before Equinox shifted the focus to Null, so highly doubt it.
EVE Frontier is completely separate and has it’s own pace. Though I do suspect there will be EVE Online tie ins for Vanguard.
Depending on who you ask, mining is actually doing well. It’s producers and buyers that are complaining about the MPI.
I think this year will be more Drifters and more Null. Drifters affecting all areas of space, and more iteration on the recent Null changes. Hopefully we will see more carrier balance, or at least a more defined role adjustment.