Agents, much like Officers or faction spawns, would regularly shuttle or fly in combat ships or with combat escorts to and from their corporations stations. While upon this route the agent could be assassinated by players.
Either an open world mission through the Agency or a Broadcast or Emergency CTA notice would appear for various capsuleers or all capsuleers. Enemies of the agent, corporation or faction would announce a bounty hit on the agent in question and the agents starting station for their journey.
Tracking down possible routes or the convoy would be entirely up to the player. And with multiple routes always available even into low sec and a time limit of the agent finishing the trip would put a time cap on things.
The mission would have profound agent, corp and faction standings hits and gain depending on who the underlying “anonymous” bidder of the contract is and due to its anonymous nature the pilot in question would have to weigh the pros and cons of such a mission. Engage and kill the agent and suddenly you might be -10 to Caldari Navy and -5 to the Caldari State but +10 to Federation Navy and +5 to the Gallentes. And because the hit is in Caldari space you have to egress from an entirely hostile faction. And all that after dispatching the escort of new AI AND the agent themselves.
The reward? A tidy sum of LP tags aboard the agents vessel in fully lootable and stolen amounts with multiple loot containers, a large loot sum from the bidder and the standings gains.
The other part of the reward is that this particular agent is no longer available to anyone for a time until they are recloned. It could be a short time for some, or a longer time, even up to a day or more.
The new AI would allow for a very interesting escort fleet for these agents. Able to call in faction security forces or even other escort ships and could make these agent assassination missions some of the hardest to pull off.
Want to disrupt agent missions in any area? Want to make a tidy sum of isk and loot doing it? Want an almost full PvP engagement against NPCs? Want an unknown ending that might set you up for life with a faction or corporation or break everything you built up for months through contacts and time?
Compete or work with those around you or even against each other. Hit accept on the mission and decide if you find your target before they reach their destination or someone else finds them first.