Generally the higher levels of research are questionable for items that are built using components rather than raw materials. You can spend a year researching a capital BPO to ME10 and end up saving nothing compared to ME9. For example: http://games.chruker.dk/eve_online/item.php?type_id=19721
You can use Chruker to see the benefit of additional research for any blueprint. Generally ME10 is worthwhile for products made from basic materials but you need to be careful for products made from components.