There are 60+ courier bots running out of Itamo IV - Moon 1 - Perkone Factory right now. They do not reply to convo, trade, or duel requests. If you bump them off the station they are trying to dock in, after 3min they relog very predictably and re-attempt to dock with the station. Running for most of the day, every day that I can observe them.
If you want to profit, keep a close eye on caldari LP as they probably generate large amounts of it, and 4+ implants as each character will likely get half a dozen over a day. Start stockpiling now when the farm does get banned a massive chunk of supply depressing the market will be gone.
As for trade bots, once you understand their overbid and undercut rules, they are very exploitable. Too loose, pump and dump them for billions in profit. Too tight, break their limit by a few 100 isk and they are effectively shut down.