I ran into the same issue and solved it today.
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I’ve backed up my profiles (%localappdata%\ccp\eve\h_eve_sharedcache_tq_tranquility{profile_name}) - * deinstalled eve
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deleted the folder %localappdata%\ccp
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deleted every eve-folder that was left after the deinstall
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opened the regedit and deleted the hive-node [HKEY_CURRENT_USER\SOFTWARE\CCP]
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reinstalled the game
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I firstly launched it with the default profile and undocked from jita 4-4 (where i got the stuttering for at least the duration of the location change timer). → no performance issues
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than i’ve copied my previous backed up settings (just the settings_* folders) into the settings folder (h_eve_sharedcache_tq_tranquility)
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linked the settings to my accounts
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tried the jita 4-4 undock test and the stuttering is gone
(note: I don’t copied the cache folder from my previous installation)