I’ve done a fair few things in game, been to/lived in every type of space and decided that whilst I don’t mind a bit of casual PVP that I prefer to make things and so eventually joined a high sec corp where I could do that. My theory then, and mainly now is to be in a core and base myself near Jita as generally (not all the time of course) the cheapest manufacturing items can be found there. I appreciate that this theory is probably flawed and certainly is limiting.
I think that it maybe my lack of understanding of Industry in general that is limiting me, but currently I have 2 trains of thought.
1: Jita seems to have for sale all the advanced components and items for T2 production and generally at the cheapest prices, if you are stuck out in null and need those items you need to either find someone locally who may have some of the items or pay for expensive JF services to bring the items to you.
2: The markets are more limiting outside the top 2 trade hubs, often when I log in and it says there is about 20k users online I often see 1800+ people in Jita, ok, not all of those are there buying but regardless that is a sizeable percentage of the online player base in 1 system.
I guess this is a long winded way of trying to find out what the advantages are for an industrialist away from the easy market (both selling and buying) that high sec offers.