My current High Sec mining mission fleet and the missions I use them for are listed below.
L4 Gas Venture
• Gas Injections
• Like Drones to a Cloud
L4 Ice Retriever (w/Medium Ice Harvester Accelerator I)
• Cheap Chills
• Ice Installation
L4 Ore Retriever
• Not Gneiss at All
L4 Ore Porpoise
• Arisite Envy
• Feeding the Giant
• Geodite and Gemology
As a general rule I will regularly decline the ‘Mother Lode’ mission and on the off chance I get it twice in a row I will just go do something else while waiting out the cool down on the penalty for declining a mission twice in four hours.