New Eden used to have 2-3 times as many logged in pilots as it does now, and even then there would be areas of space that were just empty. New regions could add a bit of a mad rush to claim new space, however you would just see more of the same power blocks just taking more and the “new” content would only see action for a short time before receding to the status quo.
We have yet to see what exactly is happening when Invasion part 2 happens and how it might change the face of New Eden. Will Drifters just start trying to take sov away? Will Triglavians start settling high and low sec areas? Not to mention how making a choice between allying the Empires and Triglavians will affect things.
All those unknowns aside, what needs to happen, is something that continually brings players out and creates conflict across a large area to try and spread out the player base. Which is a lot easier to say than to do.