Some good information thus far… let me see if I can flesh it out a bit:
1a) Yes, it is possible. They are called "Safe Spots."
While in warp you can right click in space and select create bookmark. if this option doesn’t show, go to the People and Places menu on the option bar (on your left) > Places tab > Bookmark.
Note that it makes thing easier to open this menu up before entering warp.
A few things to note though:
- Don’t view Safe Spots as truly “safe.” There are some players who specialize in finding others using ships with certain equipment (see: Expanded Probe Launcher loaded with Combat Probes).
This goes doubly so if you are in a system with a 0.4 or lower security rating (see: Low-sec, Null-sec, and Wormhole space).
- Always be in motion (preferably with a microwarpdrive if you can fit it) and “bounce” to another Safe Spot as often as you reasonably can (preferably a Safe Spot that is a few tens of AU away)
2a) Jump Fatigue is something you won’t have to deal with unless you are using…
- Jump Bridges (null-sec structure only… think player made stargate that uses fuel)
- Capital ships with their own built-in Jump Drive (same idea as a jump bridge, but jumps the whole ship to a “beacon” that is lit by another player in a destination system)
- Titan and Black-ops jump bridges (cross between a Jump Bridge and Capital Jump Drive… Titans and Black-ops can open a portal to a “beacon” in a destination system).
So what is Jump Fatigue exactly?
It is effectively 2 “timers” that come up after using/doing the aforementioned things.
The first timer will put in place a hard "you cannot perform a jump move of any kind for the next X minutes."
The second timer is much longer than the first and acts as a multiplier of the first timer (if you perform another “jump” while the second timer is up.
(Note: The reason for such a contrived mechanic is to prevent super fast travel of large amounts of “power” across the map. Large organizations became scary good at creating networks to do just this… effectively crushing anyone who happened to be on their scope with minimal effort).
I should also note that Jump fatigue has NOTHING to do with Stargates. Travel between gates is unrestricted (mechanically at least).