IV skills mean 2 extractors, each at 18k an hour, 6 P1 processors, 3 P2 processors, a launchpad.
You can do it anywhere, but WH/Null is easy to get the 18k on. In lowsec you might struggle. In highsec its probably downright impossible.
I do 24-48h resets and collect the P2 stuff and bring it to a P3 processing superplanet once every two weeks.
Key is “more P0 =/= better”. You gotta keep it as close to 18k/h as possible. If you get 24k yield, move the heads further away so you get 18.1k or so. Because the 24k yield, while technically giving you bit more money, will clutter your storage like ■■■■ with P0 junk that is heavy and nobody wants. You’ll have to cycle it more often - not worth the time or effort. So keep it close to 18k.