Interesting, this is in planetart production mode? Ccould you please send us a bug report about this, when this happens again?
On Singularity the regular EVE launcher for Mac is now starting the native Mac client and no longer the client through Wine. Check The Native Mac Client is now the default client for Singularity 🎉 for details.
YES, it does. 
We made some adjustments to keyboard shortcuts, but “Stop Ship” is still mapped to “Shift+Space”. “CTRL+Space” is unfortunately already used and so far we could not find any better replacement (but I have to agree, that I personally also still struggle with it, especially as I am constantly switching between Mac and Windows).
If you have any feedback for the keyboard shortcuts, especially on how exactly to improve them, then please write it up here: The Native Mac Client is now the default client for Singularity 🎉 If you think that any keyboard shortcut is just broken, then please also send a bug report.
As far as I know not.