Just had a buddy message me that discord overlay has been causing issues. Disabled the overlay and tentatively seems to have fixed the issue.
EDIT - This definitely fixed the issue for me.
Same!!! Just did some basic testing on multiple eve clients and disabling Discord overlay (I just turned the whole thing off) and now my clients dont fight for focus.
Clicking on a window now gives it focus and activates the UI in game.
Hero award to you.
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Seems to be working for me as well. Thank you so much 
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I am experiencing the same issue as Brilok.
Windows 11 with latest Win and EVE patch.
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Disableing Discord Overlay fixxed it for me and a buddy of mine as well.
What they said above. Still happening after DT today
Disable Discord overlay - that’s the work around.
Discord → Settings Gear Icon → Scroll Down → Look for Overlay and uncheck this so it’s off