I’ll give you some really good advise when it comes to making isk in eve. In general, the average player will have between 10-50 billion. Most players will not exceed 100b, and if they do its likely they are super-capital pilots (specifically piloting titans).
The only real ways to exceed these values are two, in general, which are running an successful entity (Alliance, or coalition), or Large scale market manipulation.
The latter is a little ambiguous, but in general it means effecting key market locations, or the over all market on a massive scale for a few items. In high sec this is largely controlled by goonswarm, as they mass produce items in null and low sec, export to high and then burn everything causing people to run to their product.
This is important to understand because this ultimately means that if you want to engage in manipulation you will need to be part of a larger entity, like one of the super-coalitions (test, nc, goons, etc), and you will need to do so in nullsec.
Now we get to this massive game of manipulating the markets and not getting caught, or finding ways to put alts in the entity, to get access to doing it again, and so on, which is another meta level of understanding the complexities of market manipulation.
IF your happy with the <100b liquid state, then its fairly easy to accomplish these amounts. For example, you can accumulate 80-120m an hour in an incursion fleet, and they are really fun (in ways very similar to pvp, its the best pve combat eve has to offer), you could also optimize in various parts of industry like production or research, or look into the null harvesting (rorq or gas farming )variants.
I’d say the average income of eve across all players added is probably in the area of 70-80m an hour. So if your not making that kind of isk you may want to look around at something else.